Publications

2011

Hewitson, J.P., Harcus, Y., Murray, J., van Aagtmaal, M., Filbey, K.J, Grainger, J.R., Bridgett, S., Blaxter,M.L., Ashton, P.D, Ashford, D., Curwen, R., Wilson, R.A., Dowle A. and Maizels, R.M. (2011) Heligmosomoides polygyrus as a model for gastrointestinal nematode infections: proteomic analysis reveals dominance of venom allergen homologues among adult excretory-secretory (HES) products. Journal of Proteomics, 74 : 1573-1594

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Maizels, R.M. and Allen, J.E. (2011) Forestalling obesity by eosinophils and helminths. Science 332 :186-187

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Maizels, R.M., Hewitson, J.P. and Gause, W.C. (2011). Heligmosomoides polygyrus: one species still. Trends in Parasitology 27: 100-101

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Mutapi, F., Bourke, C., Harcus, Y., Midzi, N., Mduluza, T., Turner, C.M., Burchmore, R. and Maizels, R.M.(2011) Differential recognition patterns of Schistosoma haematobium adult worm antigens by the human antibodies IgA, IgE, IgG1 and IgG4. Parasite Immunology 33: 181-192

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Mutapi, F., Imai, N., Nausch, N., Bourke, C., Rujeni, N., Mitchell, K., Midzi, N., Woolhouse, M., Maizels, R.M., and Mduluza, T. (2011) Autoimmune reactivity is inversely related to intensity of< schistosome infection. PLOS One 6(5) : e16860<

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Nausch, N., Midzi, N., Mduluza, T., Maizels, R.M. and Mutapi, F. (2011) Regulatory T cells in human Schistosoma haematobium infections. PLOS One 6: e1686

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Smith, K., Hochweller, K., Hammerling, G., Boon, L., MacDonald, A.S, and Maizels, R.M. (2011) Chronic helminth infection mediates tolerance in vivo through dominance of CD11clo DC population. 186:7098-7109

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Smith, K.A. and Maizels, R.M. (2011) Defeating sepsis by misleading MyD88. Nature Immunology 12:284-286

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Sutherland, T.E., Andersen, O.A., Betou, M., Eggleston, I.M., Maizels, R.M., van Aalten, D. & Allen, J.E. (2011) Analysing airway inflammation with chemical biology: functional dissection of acidic mammalian chitinase activity with a selective drug-like inhibitor. Chemistry and Biology, 18: 569-579

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Van der Werf, N., Redpath, S.A., Phythian-Adams, A.T., Azuma, M., Allen, J.E., Maizels, R.M., MacDonald, A.S and Taylor, M.D (2011) Th2 response to helminth parasites can be therapeutically enhanced by, but are not dependent upon, GITR-GITRL co-stimulation in vivo. Journal of Immunology, 187: 1411-1420

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2012

Artis, D. and Maizels, R.M. (2012) A multitasking defence Nature 484: 458-459.

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Herbst, T., Esser, J., Prati, M., Kulagin, M., Stettler, R., Zaiss, M., Hewitson, J.P., Merky, M, Verbeek, J.S., Bourquin, C., Camberis, M., Prout, M., Maizels, R.M., Graham Le Gros, G. and Harris, N.L. (2012) Antibodies and IL-3 support helminth-induced basophil expansion. Proceedings of the National Academy of Sciences USA, 109 : 14954-14959

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Hoflehner, E., Hufnagl, K, Schabussova, I, Jasinska, J., Hoffmann-Sommergruber, K., Bohle, B., Maizels, R.M. and Wiedermann, U. (2012) Prevention of birch pollen-related food allergy by mucosal treatment with multi-allergen-chimers in mice PLOS One7: e39409

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Reynolds, L.A. and Maizels, R.M. (2012) In the absence of TGF-β signaling in T cells, fewer CD103+ regulatory T cells develop, but exuberant IFN-γ production renders mice more susceptible to helminth infection. Journal of Immunology 189: 1113-1117

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Maizels, R.M. and Hewitson, J.P. (2012) Immune recognition of parasite glycans. In 'Anticarbohydrate Antibodies – From Molecular Basis to Clinical Application’ (Kosma P. & Müller-Loennies, S., Eds). Springer. ISBN 978-3-7091-0869-7, pp 161-180

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Maizels, R.M., Hewitson, J.P. and Smith, K.A. (2012) Susceptibility and immunity to helminth parasites. Current Opinion in Immunology, 24: 459-466

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Maizels, R.M., Hewitson, J.P., Murray, J., Harcus, Y., Dayer, B., Filbey, K.J., Grainger, J.R., McSorley, H.J., Reynolds, L.A. and Smith, K.A. (2012) Immune modulation and modulators in Heligmosomoides polygyrus infection. Experimental Parasitology 132: 76-89

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McSorley, H.J. and Maizels, R.M. (2012) Helminth infections and host immune regulation. Clinical Microbiology Reviews 25: 585-608

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McSorley, H.J., O’Gorman, M.T., Blair, N., Sutherland, T.E., Filbey, K.J., and Maizels, R.M. (2012) Suppression of Type 2 immunity and allergic airway inflammation by secreted products of the helminth Heligmosomoides polygyrus. European Journal of Immunology 42: in press

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Parkinson, J., Wasmuth, J., Salinas, G., Bizarro, C.V, Sanford, C., Berriman, M., Ferreira, H., Zaha, A., Blaxter, M.L., Maizels, R.M. and Fernandez, C. (2012) A transcriptomic analysis of Echinococcus granulosus larval stages: implications for parasite biology and host adaptation. PLOS Neglected Tropical Diseases, in press

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